Forgive sins: rise of thalidomide

I Will Forgive You--This Time.

Although adenocarcinoma of the prostate persists in being the most common form of cancer in men, its clinical behavior does not maintain this type of consistency, wavering from extremely aggressive fatal cancers to clinically insignificant, incidental entities. The prevalence of prostate cancer at autopsy is remarkably high, increasing from 20% in men in their 50s to up to 80% in men 70 to 80 y...

Rediscovering Thalidomide

Thalidomide, a hypnosedative drug introduced in the 1950, has been used in a variety of dermatologic conditions during the past few decades. Although originally withbrawn from world market on discovery of its teratogenic effect, it has since been selectively reintroduced for use in various disorders thought to have an autoimmune or inflammatory basis. A review of the literature focused on clini...

Thalidomide as a Potential HIV Latency Reversal Agent: Is It the Right Time to Forget the Ancestral Sins?

a YRG Centre for AIDS Research and Education (YRG CARE), VHS Hospital Campus, Taramani, Chennai 600 113, India b Lab-based Department, Royal College of Medicine Perak, Universiti Kuala Lumpur (UniKL-RCMP), Ipoh, Malaysia c Center of Excellence for Research in AIDS (CERiA), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia d Division of Infection Biology, Department of Life Scien...

To Forgive or Not to Forgive: An Analysis of U.S. Consumer Bankruptcy Choices

C urrent U.S. bankruptcy law has two separate bankruptcy procedures, known as Chapter 7 and Chapter 13. When a debtor files for bankruptcy under Chapter 7, he or she must give up all assets not legally sheltered from creditor seizure in exchange for a discharge of almost all preexisting debts. Under Chapter 13, a debtor may keep all property in exchange for a promise to pay all or some specifie...

An ABC of Prescribing Sins.